Taxonomic distribution of species displaying positive and negative associations between the presence of defense systems and the number of genes from the mobilome (based on COG annotations). Taxa discussed in the text are labeled: (A) Acinetobacter; (Pa) Pseudomonas aeruginosa; (Pv) Phocaeicola vulgatus; (Pd) Phocaeicola dorei; (S1) Streptococcus pyogenes, Streptococcus dysgalactiae, Streptococcus equi, and Streptococcus uberis; (S2) Streptococcus gordonii, Streptococcus anginosus, Streptococcus mutans, and Streptococcus salivarius; and (S3) Streptococcus oralis, Streptococcus intermedius, and Streptococcus suis. The classes Bacilli and Clostridia are the major components of the Genome Taxonomy Database phyla “Bacillota” and “Bacillota_A.” Note that, because of cross-species differences in statistical power, the condition |ES| > SSES does not necessarily imply statistical significance. For a larger version including all species names, see Supplemental Figure S3.
