Ultraviolet damage and repair maps in Drosophila reveal the impact of domain-specific changes in nucleosome repeat length on repair efficiency

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Figure 4.
Figure 4.

CPD repair activity exhibits a translational nucleosome periodicity that is inconsistent across different chromatin types. (A,B) Relative CPD enrichment (A) and repair (30 min; B) trends with respect to translational nucleosome positioning. (A) CPD enrichment is normalized to a UV-exposed, naked DNA control. (B) Repair data are normalized to cellular damage data. (C) Lomb–Scargle periodogram of translational nucleosome periodicities for CPD damage and repair. The damage and repair periodicities were derived from the data plotted in A and B, respectively. (D) CPD repair activity within 1000 bp of nucleosome dyads, stratified by chromatin type and time point. The data in C were scaled for each subplot so that they have a uniform mean of one.

This Article

  1. Genome Res. 35: 257-267

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