Figure 3.
Repair of CPDs is faster in linker DNA regardless of chromatin state. (A,B) Relative CPD enrichment (A) and repair activity (30 min; B) with respect to rotational nucleosome positioning. The CPD enrichment data used to generate plot A are the same as in Fig. 1C, but both axes have been expanded to include linker DNA and highlight differences in amplitude compared with repair data (B). (A) CPD enrichment is normalized to a UV-exposed, naked DNA control. (B) Repair data are normalized to cellular damage data. (C) CPD repair activity within 103 bp of nucleosome dyads, stratified by chromatin type and time point. The data in C were scaled for each subplot so that they have a uniform mean of one.
