FocalSV enables target region–based structural variant assembly and refinement using single-molecule long-read sequencing data

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Figure 6.
Figure 6.

Insertion F1 accuracy of FocalSV(auto) by tuning different evaluation parameters (p and r). r is the maximum reference location distance between SV call and gold standard SV. p is the minimum percentage of allele sequence similarity between SV call and gold standard SV. p vary from 0 to 1 with a 0.1 interval. r varies from 0 to 1000 bp with a 100 bp interval. (AC) The F1 heat map for insertions by FocalSV(auto) on three HiFi data sets. Every cell in the heat map represents the F1 score under a specific pair of p and r evaluation. (DF) The F1 heat map for insertions by FocalSV(auto) on three CLR data sets. (GI) The F1 heat map for insertions by FocalSV(auto) on three ONT data sets.

This Article

  1. Genome Res. 35: 2252-2272

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