Chimeric mitochondrial RNA transcripts predict mitochondrial genome deletion mutations in mitochondrial genetic diseases and aging

Table 3.

Chimeric mtRNA frequency in human aging brain samples

Database
Experimental group (n) Average base pairs sequenced Chimeric mtRNA FFPM MT-CO1, 2, 3-MT-CYB chimeric mtRNA FFPM
Human aging brain
(GSE68719) 		8.5 ± 0.3 × 109
46–97 years old (73) 22.99 ± 1.69 0.93 ± 0.077

  • (n) Number of human subjects. Data shown are mean ± SEM.

This Article

  1. Published in Advance November 27, 2024, doi: 10.1101/gr.279072.124 Genome Res. 35: 55-65

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