Table 2.
Chimeric mtRNA frequency in human aging muscle samples
| Database | |||
|---|---|---|---|
| Experimental group (n) | Average base pairs sequenced | Chimeric mtRNA FFPM | MT-CO1, 2, 3-MT-CYB chimeric mtRNA FFPM |
| Human aging muscle (GSE157585) |
1.4 ± 0.03 × 1010 | ||
| 20–30 years old (21) | 40.4 ± 4.02a | 1.16 ± 0.12b | |
| 65–91 years old (50) | 71.5 ± 5.11a | 2.82 ± 0.24b |
-
(n) Number of human subjects. Data shown are mean ± SEM.
-
aP-value = 6.4 × 10−6 using Welch's two-sample t-test.
-
bP-value = 7.3 × 10−9 using Welch's two-sample t-test.
