Post-transcriptional cross- and auto-regulation buffer expression of the human RNA helicases DDX3X and DDX3Y

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Figure 6.
Figure 6.

DDX3X mRNA stability is regulated. (A) Schematic of experiment to determine half-lives of mRNAs. 46,XY and 49,XYYYY LCLs were incubated with 5-ethyl uridine (5-EU) to obtain nascent mRNAs. (B) DDX3X has an mRNA half-life of 0.5 h in 49,XYYYY versus 1.3 h in 46,XY LCLs.

This Article

  1. Published in Advance January 10, 2025, doi: 10.1101/gr.279707.124 Genome Res. 35: 20-30

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