Figure 4.
Human hyperfunctioning PT gland single-cell RNA sequencing. (A) Histology of tissue sections from the samples from which sequencing libraries were derived (H&E stain; scale bar, 30 µm). (B) PHATE embedding of filtered human cells colored by cluster number and PTH expression in the human single-cell data set. (C) Dot plot representing the frequency and expression levels of the top eight differentially expressed genes between clusters. (D) Human PT cells (cluster 1) subsetted from the original data set and re-embedded with PHATE, colored by sample origin. (E) Embedding colored by expression of PT-relevant genes in PHATE plots.
