A systematic review on the biochemical threshold of mitochondrial genetic variants

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Figure 4.
Figure 4.

Complex I structure. The complex I structure with the mtDNA-encoded subunits (MT-ND1-4, MT-ND4L, MT-ND5-6) highlighted. An enlarged image indicates of the location of the m.13513G > A variant that results in an Asp393Asn within an alpha helix (PBD ID: 5XTD) (Guo et al. 2017).

This Article

  1. Published in Advance April 16, 2024, doi: 10.1101/gr.278200.123 Genome Res. 34: 341-365

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