Table 1.
The Integrative Catalog in human 3D structure generated from this study aggregates Hi-C data from multiple projects
| Studies | # Samples | # Total sequenced reads | Resolutions (bp) | # TADs | # Loops |
|---|---|---|---|---|---|
| HGSVC2 (Ebert et al. 2021) | 27 | 250,215,126–846,623,607 | 4650–17,800 | 18,865 | 28,340 |
| HGSVC1(Gorkin et al. 2019) | 9 (three overlapped with HGSVC2) | 453,690,983–750,185,985 | 10,500–13,300 | ||
| 4DN (Dekker et al. 2017) | 10 | 429,572,702–868,174,924 | 9800–14,700 | ||
| GM12878 (Rao et al. 2014) | 1 | 6,524,520,477 | 950 |
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The Hi-C data from 44 individuals collected in this study were obtained from the HGSVC2 (Ebert et al. 2021), HGSVC1 (Gorkin et al. 2019), 4DN project (Dekker et al. 2017), and GM12878 (Rao et al. 2014) (with the highest resolution). Three samples (HG00514, HG00733, and NA19240) from HGSVC1 were resequenced in HGSVC2 at a higher resolution; thus, we retained those samples from HGSVC2 for further analysis. Resolutions were calculated for each sample, and the TADs and loops were called on the merged data set of 44 samples.
