
Host and nested gene expression profiles and tissue specificity. (A) Distribution of the expression of all, host, and nested genes for the biotypes associated with the three categories in human and mouse transcriptomes (B) Distribution of τ index calculated using the normalized expression level detected in RNA sequencing data sets. The higher the value of τ the more the gene exhibits tissue-specific expression. Across 1000 matched-size random samples, the application of a Kolmogorov–Smirnov test to these distributions always resulted in a P < 0.05. The figure shows one representative matched sample comparison.











