Sergey Koren; Zhigui Bao; Andrea Guarracino; Shujun Ou; Sara Goodwin; Katharine M. Jenike; Julian Lucas; Brandy McNulty; Jimin Park; Mikko Rautiainen; Arang Rhie; Dick Roelofs; Harrie Schneiders; Ilse Vrijenhoek; Koen Nijbroek; Olle Nordesjo; Sergey Nurk; Mike Vella; Katherine R. Lawrence; Doreen Ware; Michael C. Schatz; Erik Garrison; Sanwen Huang; William Richard McCombie; Karen H. Miga; Alexander H.J. Wittenberg; Adam M. Phillippy

Gapless assembly of complete human and plant chromosomes using only nanopore sequencing

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 2.

Duplex data from ONT is accurate and long. A comparison of human HG002 sequencing read length and quality for ONT Duplex (this paper) and PacBio HiFi (https://downloads.pacbcloud.com/public/revio/2022Q4/) Phred QV was measured as in Nurk et al. (2020), using the finished X Chromosome from HG002 as a ground truth (Nurk et al. 2020; Rhie et al. 2023). Plotted using R (R Core Team 2024) and ggplot2 (Wickham 2016).