Theoretical framework for the difference of two negative binomial distributions and its application in comparative analysis of sequencing data

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Figure 1.
Figure 1.

Computational workflow of DEGage. DEGage takes two scRNA-seq data sets as inputs and utilizes the DOTNB distribution as the core statistical model to test the significance of gene expression profiles of the two data sets. It outputs multiple types of information suitable for downstream analysis.

This Article

  1. Published in Advance October 15, 2024, doi: 10.1101/gr.278843.123 Genome Res. 34: 1636-1650

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