Figure 2.
ASm6A profiling in human tissues. (A) Numbers of ASm6As identified in 25 human tissues. (B) ASm6A modification at the rs1130635 locus in three different tissue samples from the same individual. The horizontal coordinate represents the genomic position, and the vertical coordinate represents the number of sequence reads supporting two alleles (T and C) in the IP sample. The T/C read counts in input samples were 40/36, 26/31, and 40/45 in Cerebellum-3, Heart-3, and Liver-3, respectively. (C) MeRIP followed by Sanger sequencing showing the relative m6A level of allele 2 versus allele 1 at genes in the Kidney-2 sample.
