Targeted, programmable, and precise tandem duplication in the mammalian genome

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Figure 5.
Figure 5.

Applications of TD-PE in the investigation of disease-relevant TDs. (A) PegRNAs design at the ENG site and the putative editing process of TD-PE strategy. (B) Agarose gel electrophoresis analysis of the presence of TD at four disease-related loci. (C) Quantification of the efficiency of targeted TD in B. Values and error bars reflect mean ± SD of n = 3 independent biological replicates.

This Article

  1. Published in Advance June 9, 2023, doi: 10.1101/gr.277261.122 Genome Res. 33: 779-786

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