Characterization of differentially expressed genes (DEGs) between PS-HET and Control-HET. (A) A modified volcano plot depicts the log2(posterior fold change; x-axis) versus the posterior probability of differential expression (y-axis). Open circles (red/black) represent each gene examined, and differentially expressed genes (red) are shown above the significance line (blue; FDR P-value < 0.1). (B,C) A bar plot showing the top significantly overrepresented GO terms based on GO analysis of PS-HET-specific (B) differentially expressed genes and Control-HET-specific (C) differentially expressed genes. The number of DEGs linked to the GO terms are displayed on the x-axis. Bar color is based on P-value. (D) A Venn diagram depicts the overlap of DhMR-associated genes (green circle) and differentially expressed genes (orange circle) from the PS-HET versus Control-HET comparison. The asterisk (*) denotes a significant overlap (hypergeometric enrichment P-value < 0.05).
