Non-Mendelian inheritance patterns and extreme deviation rates of CGG repeats in autism

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Figure 5.
Figure 5.

Based on the informative genotypes, when parents displayed heterozygous repeat length genotypes at given CGG locus the times the smaller and larger repeats were transferred to the child for cohorts total (A), NGC trios (B), MSSNG trios (C), and MSSNG quads (D). Although total observations differed from cohort to cohort, the same proportional trend of larger to smaller allele transfers was consistent across all trios, as was the trend of no difference between the total transfer observations of mothers and fathers.

This Article

  1. Genome Res. 32: 1967-1980

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