Figure 1.
Distribution and deviation rate of known CGG short tandem repeats (STRs) throughout the human genome. Genomic positioning (GRCh38) and HGNC gene symbols where the hypermutable CGG STRs are localized. (A) Deviation rate of all known polymorphic CGG repeats: (hypermutable) ≥3 × 10−1 deviations per gamete per generation, (intermediate) ≥1 × 10−2 deviations per gamete per generation, and (normal) more than zero deviations per gamete per generation. (B) Average repeat length deviation for both expansions and contractions of each polymorphic CGG STR locus (CGG repeat units) (Gu et al. 2014).
