Figure 5.
Spatial organization of loci previously associated with X Chromosome structural organization. (A) Hi-C contact map of the domestic cat inactive X Chromosome reveals conservation of the unique bipartite structural conformation and role of DXZ4 as a hinge region between superdomains (resolution = 500 kb, balanced normalization). (B) Interspecific comparison of long-range interacting loci reveals that relative position and linear spacing along the X Chromosome is conserved across highly divergent mammalian clades.
