Modeling expression ranks for noise-tolerant differential expression analysis of scRNA-seq data

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Figure 2.
Figure 2.

Benchmarking of single-cell DE call accuracy against DE genes detected at tissue levels. (A) ROC and the associated AUC values obtained by bulk-based benchmarking of single-cell DEG calls between BJ and K562 cells (Gupta data). (B) ROC plot for H1 and H9 cells (source: Chu data) (Chu et al. 2016). (C) ROC plot for NA19098 and NA19239 cells (source: Tung data) (Tung et al. 2017).

This Article

  1. Published in Advance March 5, 2021, doi: 10.1101/gr.267070.120 Genome Res. 31: 689-697

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