Improved redox homeostasis owing to the up-regulation of one-carbon metabolism and related pathways is crucial for yeast heterosis at high temperature

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Figure 6.
Figure 6.

Effects of ADE3 gene deletion on the growth and cellular oxidative stress of F1 hybrids of wild S. cerevisiae at 40°C. (A) Growth curves of wild types (WTs) and ade3Δ/Δ mutants of four F1 hybrids without or with 15 mM N-acetyl-L-cysteine (NAC) in the medium. (B) MGRs of wild types and ade3Δ/Δ mutants of four F1 hybrids without or with 15 mM NAC in the medium. (C) Comparisons of cellular ROS levels (left) and NADP+/NADPH ratios (right) between the wild types and ade3Δ/Δ mutants of four F1 hybrids. (*) P < 0.05; (**) P < 0.01; (***) P < 0.001; (NS) not significant, P > 0.05 (Mann–Whitney U test). Error bars, SDs (n ≥ 3).

This Article

  1. Published in Advance March 15, 2021, doi: 10.1101/gr.262055.120 Genome Res. 31: 622-634

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