Figure 3.
Conservation of distinct classes of TAD boundaries between D. melanogaster and D. pseudoobscura. (A) Boundaries that overlap with binding sites of architectural proteins versus those lacking the corresponding binding sites. (B) Boundaries linked with active TADs versus inactive TADs. (C) Boundaries that share across cell lines versus cell-line-specific boundaries. (D) Strong versus weak boundaries. Statistical significance were calculated using chi-square test: (***) P < 0.001; (**) P < 0.01; (NS) no significance (for details, see Supplemental Table S14).
