Blood-derived mitochondrial DNA copy number is associated with gene expression across multiple tissues and is predictive for incident neurodegenerative disease

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Figure 1.
Figure 1.

Global inflation of test statistics from linear regressions between blood-derived mtDNA-CN and gene expression in blood. After stratification by gene category, protein-coding genes have the most inflation, suggesting that mtDNA-CN is strongly associated with genes that code for proteins.

This Article

  1. Published in Advance January 13, 2021, doi: 10.1101/gr.269381.120 Genome Res. 31: 349-358

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