Volume 29, Issue 8 | August 2019

Research
- - High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma
    Michael J. Johnston
    Ana Nikolic
    Nicoletta Ninkovic
    Paul Guilhamon
    Florence M.G. Cavalli
    Steven Seaman Franz J. Zemp John Lee Aly Abdelkareem Katrina Ellestad Alex Murison Michelle M. Kushida Fiona J. Coutinho Yussanne Ma Andrew J. Mungall Richard Moore Marco A. Marra Michael D. Taylor Peter B. Dirks Trevor J. Pugh Sorana Morrissy
    ...[+16 authors]...,
    Bradley St Croix
    Douglas J. Mahoney
    Mathieu Lupien
    Marco Gallo
    First Published June 27, 2019
  - Glucocorticoid receptor quaternary structure drives chromatin occupancy and transcriptional outcome
    Ville Paakinaho
    Thomas A. Johnson
    Diego M. Presman
    Gordon L. Hager
    First Published July 23, 2019
  - Two contrasting classes of nucleolus-associated domains in mouse fibroblast heterochromatin
    Anastassiia Vertii
    Jianhong Ou
    Jun Yu
    Aimin Yan
    Hervé Pagès
    First Published June 14, 2019
  - Whole-genome sequencing reveals high complexity of copy number variation at insecticide resistance loci in malaria mosquitoes
    Eric R. Lucas
    Alistair Miles
    Nicholas J. Harding
    Chris S. Clarkson
    Mara K.N. Lawniczak
    First Published July 25, 2019
  - Circadian gene variants and the skeletal muscle circadian clock contribute to the evolutionary divergence in longevity across Drosophila populations
    Liam C. Hunt
    Jianqin Jiao
    Yong-Dong Wang
    David Finkelstein
    Deepti Rao
    Michelle Curley Maricela Robles-Murguia Abbas Shirinifard
    ...[+3 authors]...,
    Vishwajeeth R. Pagala
    Junmin Peng
    Yiping Fan
    Fabio Demontis
    First Published June 27, 2019
  - Capture of a functionally active methyl-CpG binding domain by an arthropod retrotransposon family
    Alex de Mendoza
    Jahnvi Pflueger
    Ryan Lister
    First Published June 25, 2019
  - Characterization of functional relationships of R-loops with gene transcription and epigenetic modifications in rice
    Yuan Fang
    Lifen Chen
    Kande Lin
    Yilong Feng
    Pengyue Zhang
    Xiucai Pan Jennifer Sanders Yufeng Wu Xiu-e Wang
    ...[+4 authors]...,
    Zhen Su
    Caiyan Chen
    Hairong Wei
    Wenli Zhang
    First Published July 1, 2019
  - Local features determine Ty3 targeting frequency at RNA polymerase III transcription start sites
    Kurt Patterson
    Farbod Shavarebi
    Christophe Magnan
    Ivan Chang
    Xiaojie Qi
    First Published June 27, 2019
Methods
- - Estimation of allele-specific fitness effects across human protein-coding sequences and implications for disease
    Yi-Fei Huang
    Adam Siepel
    First Published June 27, 2019
  - Efficient and flexible tagging of endogenous genes by homology-independent intron targeting
    Yevgeniy V. Serebrenik
    Stephanie E. Sansbury
    Saranya Santhosh Kumar
    Jorge Henao-Mejia
    Ophir Shalem
    First Published June 25, 2019
  - Single-molecule long-read sequencing reveals the chromatin basis of gene expression
    Yunhao Wang
    Anqi Wang
    Zujun Liu
    Andrew L. Thurman
    Linda S. Powers
    Meng Zou Yue Zhao
    ...[+2 authors]...,
    Adam Hefel
    Yunyi Li
    Joseph Zabner
    Kin Fai Au
    First Published June 14, 2019
  - A novel synthetic-genetic-array–based yeast one-hybrid system for high discovery rate and short processing time
    Chung-Shu Yeh
    Zhifeng Wang
    Fang Miao
    Hongyan Ma
    Chung-Ting Kao
    Tzu-Shu Hsu Jhong-He Yu Er-Tsi Hung Chia-Chang Lin Chen-Yu Kuan Ni-Chiao Tsai Chenguang Zhou Guan-Zheng Qu Jing Jiang Guifeng Liu Jack P. Wang
    ...[+11 authors]...,
    Wei Li
    Vincent L. Chiang
    Tien-Hsien Chang
    Ying-Chung Jimmy Lin
    First Published June 11, 2019
  - BiosyntheticSPAdes: reconstructing biosynthetic gene clusters from assembly graphs
    Dmitry Meleshko
    Hosein Mohimani
    Vittorio Tracanna
    Iman Hajirasouliha
    Marnix H. Medema
    First Published June 3, 2019
Resource
- - Benchmark and integration of resources for the estimation of human transcription factor activities
    Luz Garcia-Alonso
    Christian H. Holland
    Mahmoud M. Ibrahim
    Denes Turei
    Julio Saez-Rodriguez
    First Published July 24, 2019

Table of Contents

Volume 29, Issue 8 | August 2019

Research

High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma

Glucocorticoid receptor quaternary structure drives chromatin occupancy and transcriptional outcome

Two contrasting classes of nucleolus-associated domains in mouse fibroblast heterochromatin

Whole-genome sequencing reveals high complexity of copy number variation at insecticide resistance loci in malaria mosquitoes

Circadian gene variants and the skeletal muscle circadian clock contribute to the evolutionary divergence in longevity across Drosophila populations

Capture of a functionally active methyl-CpG binding domain by an arthropod retrotransposon family

Characterization of functional relationships of R-loops with gene transcription and epigenetic modifications in rice

Local features determine Ty3 targeting frequency at RNA polymerase III transcription start sites

Methods

Estimation of allele-specific fitness effects across human protein-coding sequences and implications for disease

Efficient and flexible tagging of endogenous genes by homology-independent intron targeting

Single-molecule long-read sequencing reveals the chromatin basis of gene expression

A novel synthetic-genetic-array–based yeast one-hybrid system for high discovery rate and short processing time

BiosyntheticSPAdes: reconstructing biosynthetic gene clusters from assembly graphs

Resource

Benchmark and integration of resources for the estimation of human transcription factor activities

Table of Contents

Volume 29, Issue 8 | August 2019

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Research

Methods

Resource