Figure 1.
CB2 offers robust target identification with high precision and recall. (A,B) Benchmark results using data from Evers et al. (2016). (A) Heatmaps illustrate FDRs of gene statistics from each of nine leading high-complexity pooled screen analysis tools. (B) F1-score measurements at different FDR cut-offs across all methods. At commonly used FDR cut-offs, CB2 can identify most of the essential genes with high rates of precision and recall. (C,D) Same representation as in A and B, using data from Sanson et al. (2018).
