Figure 1.
The overall architecture of GenTree. It integrates three types of data: (1) gene annotation data from Ensembl; (2) gene age inference and origination mechanism inference data; and (3) gene function information based on either functional genomic data including Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx), Human Proteome Map (HPM) and BrainSpan (http://www.brainspan.org) data, quantitative genetic data (genome-wide association data from GWASdb2), and selection data (positive selection tracks from PopHuman).
