Volume 28, Issue 3 | March 2018

Research
- - A human-specific switch of alternatively spliced AFMID isoforms contributes to TP53 mutations and tumor recurrence in hepatocellular carcinoma
    Kuan-Ting Lin
    Wai Kit Ma
    Juergen Scharner
    Yun-Ru Liu
    Adrian R. Krainer
    First Published February 15, 2018
  - 3′ UTR lengthening as a novel mechanism in regulating cellular senescence
    Meng Chen
    Guoliang Lyu
    Miao Han
    Hongbo Nie
    Ting Shen
    Wei Chen Yichi Niu Yifan Song Xueping Li Huan Li Xinyu Chen Ziyue Wang Zheng Xia Wei Li Xiao-Li Tian Chen Ding Jun Gu Yufang Zheng Xinhua Liu
    ...[+14 authors]...,
    Jinfeng Hu
    Gang Wei
    Wei Tao
    Ting Ni
    First Published February 12, 2018
  - Thrombopoietin signaling to chromatin elicits rapid and pervasive epigenome remodeling within poised chromatin architectures
    Federico Comoglio
    Hyun Jung Park
    Stefan Schoenfelder
    Iros Barozzi
    Daniel Bode
    First Published February 2, 2018
  - ZFX acts as a transcriptional activator in multiple types of human tumors by binding downstream from transcription start sites at the majority of CpG island promoters
    Suhn Kyong Rhie
    Lijun Yao
    Zhifei Luo
    Heather Witt
    Shannon Schreiner
    First Published February 2, 2018
  - Relationship between histone modifications and transcription factor binding is protein family specific
    Beibei Xin
    Remo Rohs
    First Published January 11, 2018
  - Enhancer RNA profiling predicts transcription factor activity
    Joseph G. Azofeifa
    Mary A. Allen
    Josephina R. Hendrix
    Timothy Read
    Jonathan D. Rubin
    First Published February 15, 2018
  - Targeted deletion of a 170-kb cluster of LINE-1 repeats and implications for regional control
    Miguel L. Soares
    Carol A. Edwards
    Frances L. Dearden
    Sacri R. Ferrón
    Scott Curran
    Jennifer A. Corish Rebecca C. Rancourt Sarah E. Allen Marika Charalambous
    ...[+4 authors]...,
    Malcolm A. Ferguson-Smith
    Willem Rens
    David J. Adams
    Anne C. Ferguson-Smith
    First Published January 24, 2018
  - Widespread and precise reprogramming of yeast protein–genome interactions in response to heat shock
    Vinesh Vinayachandran
    Rohit Reja
    Matthew J. Rossi
    Bongsoo Park
    Lila Rieber
    First Published February 14, 2018
Methods
- - CRISPR RNAs trigger innate immune responses in human cells
    Sojung Kim
    Taeyoung Koo
    Hyeon-Gun Jee
    Hee-Yeon Cho
    Gyeorae Lee
    First Published February 22, 2018
  - Targeting mutant KRAS with CRISPR-Cas9 controls tumor growth
    Wonjoo Kim
    Sangeun Lee
    Han Sang Kim
    Minjung Song
    Yong Hoon Cha
    Young-Hoon Kim Jeonghong Shin Eun-Seo Lee Yeonsoo Joo Jae J. Song Eun Ju Choi Jae W. Choi Jinu Lee Moonkyung Kang Jong In Yook
    ...[+10 authors]...,
    Min Goo Lee
    Yeon-Soo Kim
    Soonmyung Paik
    Hyongbum (Henry) Kim
    First Published January 11, 2018
  - Reconstructing differentiation networks and their regulation from time series single-cell expression data
    Jun Ding
    Bruce J. Aronow
    Naftali Kaminski
    Joseph Kitzmiller
    Jeffrey A. Whitsett
    First Published January 9, 2018
  - SQANTI: extensive characterization of long-read transcript sequences for quality control in full-length transcriptome identification and quantification
    Manuel Tardaguila
    Lorena de la Fuente
    Cristina Marti
    Cécile Pereira
    Francisco Jose Pardo-Palacios
    Hector del Risco Marc Ferrell Maravillas Mellado Marissa Macchietto Kenneth Verheggen Mariola Edelmann Iakes Ezkurdia Jesus Vazquez Michael Tress Ali Mortazavi
    ...[+10 authors]...,
    Lennart Martens
    Susana Rodriguez-Navarro
    Victoria Moreno-Manzano
    Ana Conesa
    First Published February 9, 2018
  - FIND: difFerential chromatin INteractions Detection using a spatial Poisson process
    Mohamed Nadhir Djekidel
    Yang Chen
    Michael Q. Zhang
    First Published February 12, 2018

Table of Contents

Volume 28, Issue 3 | March 2018

Research

A human-specific switch of alternatively spliced AFMID isoforms contributes to TP53 mutations and tumor recurrence in hepatocellular carcinoma

3′ UTR lengthening as a novel mechanism in regulating cellular senescence

Thrombopoietin signaling to chromatin elicits rapid and pervasive epigenome remodeling within poised chromatin architectures

ZFX acts as a transcriptional activator in multiple types of human tumors by binding downstream from transcription start sites at the majority of CpG island promoters

Relationship between histone modifications and transcription factor binding is protein family specific

Enhancer RNA profiling predicts transcription factor activity

Targeted deletion of a 170-kb cluster of LINE-1 repeats and implications for regional control

Widespread and precise reprogramming of yeast protein–genome interactions in response to heat shock

Methods

CRISPR RNAs trigger innate immune responses in human cells

Targeting mutant KRAS with CRISPR-Cas9 controls tumor growth

Reconstructing differentiation networks and their regulation from time series single-cell expression data

SQANTI: extensive characterization of long-read transcript sequences for quality control in full-length transcriptome identification and quantification

FIND: difFerential chromatin INteractions Detection using a spatial Poisson process

Table of Contents

Volume 28, Issue 3 | March 2018

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Research

Methods