HD-Marker: a highly multiplexed and flexible approach for targeted genotyping of more than 10,000 genes in a single-tube assay

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Figure 2.
Figure 2.

Chromosomal distribution (A,C,E,G) and sequencing coverage (B,D,F,H) of target SNP markers for four multiplex levels. Extremely high capture rate (∼98%–99%) and even sequencing coverage across loci are observed for all multiplex levels. (A,B) 296-plex; (C,D) 795-plex; (E,F) 1293-plex; (G,H) 12,472-plex.

This Article

  1. Published in Advance November 8, 2018, doi: 10.1101/gr.235820.118 Genome Res. 28: 1919-1930

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