
The probability of individual genes with at least one critical loss-of-function mutation during the population expansion from a single cell. (A) The probability distribution of the ∼6000 yeast genes (y-axis) as a function of the ending population size N (x-axis). The probabilities have no apparent increase after the N reaches 6 × 107. (B) The probability distribution (y-axis) as a function of the gene length (x-axis) when N = 6 × 107. The number of genes in each length category is shown next to the box.











