The nonessentiality of essential genes in yeast provides therapeutic insights into a human disease

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Figure 2.
Figure 2.

The probability of individual genes with at least one critical loss-of-function mutation during the population expansion from a single cell. (A) The probability distribution of the ∼6000 yeast genes (y-axis) as a function of the ending population size N (x-axis). The probabilities have no apparent increase after the N reaches 6 × 107. (B) The probability distribution (y-axis) as a function of the gene length (x-axis) when N = 6 × 107. The number of genes in each length category is shown next to the box.

This Article

  1. Genome Res. 26: 1355-1362

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