Loss of HP1 causes depletion of H3K27me3 from facultative heterochromatin and gain of H3K27me2 at constitutive heterochromatin

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Figure 3.
Figure 3.

Effect of DCDC mutations on the distribution of H3K27me2/3. H3K27me2/3 ChIP-seq data are shown for two chromosomes of wild type (black line) and strains bearing deletions of dim-5 (light blue line), dim-7L448*, dim-9, dim-8, and cul4 (each indicated by red lines). All show redistribution of H3K27me2/3 to constitutive heterochromatin, with minor variations between mutants. The scale bar (500 kb) applies to both chromosomes. Data for all other chromosomes are presented in Supplemental Figure S1A.

This Article

  1. Genome Res. 26: 97-107

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