Volume 25, Issue 10 | October 2015

Preface
- - 20 Years of Genome Research
    First Published October 1, 2015
Perspectives
- - A vision for ubiquitous sequencing
    Yaniv Erlich
    First Published October 1, 2015
  - Biological data sciences in genome research
    Michael C. Schatz
    First Published October 1, 2015
  - Parlez-vous VUS?
    Gregory M. Cooper
    First Published October 1, 2015
  - Functional genomics bridges the gap between quantitative genetics and molecular biology
    Tuuli Lappalainen
    First Published October 1, 2015
  - Genomic approaches for understanding the genetics of complex disease
    William L. Lowe
    Timothy E. Reddy
    First Published October 1, 2015
  - Enabling functional genomics with genome engineering
    Isaac B. Hilton
    Charles A. Gersbach
    First Published October 1, 2015
  - Linking RNA biology to lncRNAs
    Loyal A. Goff
    John L. Rinn
    First Published October 1, 2015
  - Half dozen of one, six billion of the other: What can small- and large-scale molecular systems biology learn from one another?
    Ian A. Mellis
    Arjun Raj
    First Published October 1, 2015
  - The Mendelian disorders of the epigenetic machinery
    Hans Tomas Bjornsson
    First Published October 1, 2015
  - Epigenomics and the structure of the living genome
    Nir Friedman
    Oliver J. Rando
    First Published October 1, 2015
  - Defining cell types and states with single-cell genomics
    Cole Trapnell
    First Published October 1, 2015
  - The first five years of single-cell cancer genomics and beyond
    Nicholas E. Navin
    First Published October 1, 2015
  - The path to routine use of genomic biomarkers in the cancer clinic
    Paul C. Boutros
    First Published October 1, 2015
  - The intersection of microbiome and host at the skin interface: genomic- and metagenomic-based insights
    Elizabeth A. Grice
    First Published October 1, 2015
Research
- - Signatures of post-zygotic structural genetic aberrations in the cells of histologically normal breast tissue that can predispose to sporadic breast cancer
    Lars A. Forsberg
    Chiara Rasi
    Gyula Pekar
    Hanna Davies
    Arkadiusz Piotrowski
    Devin Absher Hamid Reza Razzaghian Aleksandra Ambicka Krzysztof Halaszka Marcin Przewoźnik Anna Kruczak Geeta Mandava Saichand Pasupulati Julia Hacker K. Reddy Prakash Ravi Chandra Dasari Joey Lau Nelly Penagos-Tafurt Helena M. Olofsson Gunilla Hallberg Piotr Skotnicki Jerzy Mituś Jaroslaw Skokowski Michal Jankowski Ewa Śrutek Wojciech Zegarski
    ...[+21 authors]...,
    Eva Tiensuu Janson
    Janusz Ryś
    Tibor Tot
    Jan P. Dumanski
    First Published October 1, 2015
  - Widespread somatic L1 retrotransposition occurs early during gastrointestinal cancer evolution
    Adam D. Ewing
    Anthony Gacita
    Laura D. Wood
    Florence Ma
    Dongmei Xing
    Min-Sik Kim Srikanth S. Manda Gabriela Abril Gavin Pereira Alvin Makohon-Moore Leendert H.J. Looijenga Ad J.M. Gillis Ralph H. Hruban Robert A. Anders Katharine E. Romans Akhilesh Pandey Christine A. Iacobuzio-Donahue
    ...[+12 authors]...,
    Bert Vogelstein
    Kenneth W. Kinzler
    Haig H. Kazazian
    Szilvia Solyom
    First Published August 10, 2015
  - The frequent evolutionary birth and death of functional promoters in mouse and human
    Robert S. Young
    Yoshihide Hayashizaki
    Robin Andersson
    Albin Sandelin
    Hideya Kawaji
    Masayoshi Itoh Timo Lassmann
    ...[+2 authors]...,
    Piero Carninci
    Wendy A. Bickmore
    Alistair R. Forrest
    Martin S. Taylor
    First Published July 30, 2015
  - Genetic and environmental control of host-gut microbiota interactions
    Elin Org
    Brian W. Parks
    Jong Wha J. Joo
    Benjamin Emert
    William Schwartzman
    Eun Yong Kang Margarete Mehrabian Calvin Pan Rob Knight
    ...[+4 authors]...,
    Robert Gunsalus
    Thomas A. Drake
    Eleazar Eskin
    Aldons J. Lusis
    First Published August 10, 2015
Methods
- - Read clouds uncover variation in complex regions of the human genome
    Alex Bishara
    Yuling Liu
    Ziming Weng
    Dorna Kashef-Haghighi
    Daniel E. Newburger
    First Published August 18, 2015
  - CETCh-seq: CRISPR epitope tagging ChIP-seq of DNA-binding proteins
    Daniel Savic
    E. Christopher Partridge
    Kimberly M. Newberry
    Sophia B. Smith
    Sarah K. Meadows
    First Published September 9, 2015

Table of Contents

Volume 25, Issue 10 | October 2015

Preface

20 Years of Genome Research

Perspectives

A vision for ubiquitous sequencing

Biological data sciences in genome research

Parlez-vous VUS?

Functional genomics bridges the gap between quantitative genetics and molecular biology

Genomic approaches for understanding the genetics of complex disease

Enabling functional genomics with genome engineering

Linking RNA biology to lncRNAs

Half dozen of one, six billion of the other: What can small- and large-scale molecular systems biology learn from one another?

The Mendelian disorders of the epigenetic machinery

Epigenomics and the structure of the living genome

Defining cell types and states with single-cell genomics

The first five years of single-cell cancer genomics and beyond

The path to routine use of genomic biomarkers in the cancer clinic

The intersection of microbiome and host at the skin interface: genomic- and metagenomic-based insights

Research

Signatures of post-zygotic structural genetic aberrations in the cells of histologically normal breast tissue that can predispose to sporadic breast cancer

Widespread somatic L1 retrotransposition occurs early during gastrointestinal cancer evolution

The frequent evolutionary birth and death of functional promoters in mouse and human

Genetic and environmental control of host-gut microbiota interactions

Methods

Read clouds uncover variation in complex regions of the human genome

CETCh-seq: CRISPR epitope tagging ChIP-seq of DNA-binding proteins

Table of Contents

Volume 25, Issue 10 | October 2015

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Preface

Perspectives

Research

Methods