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Cover From multiple perspectives, transposons and classical genes can be seen in conflict. One famous example of this is how transposons can repress gene expression through inducing DNA methylation of nearby genic sequences. Surprisingly, investigation of whole-genome DNA methylation patterns in maize (presented in this issue) reveals that genes can also induce methylation of nearby transposons. This strategy is reminiscent of a key concept in the martial arts developed by the Samurai for fighting in close quarters in which large weapons were ineffective: to take advantage of the enemies′ own strength and turn it against them. (Cover illustration by Elizabeth Lowry. [For details, see Gent et al., pp. 628–637.])