Figure 5.
Unique behavior of the HSC82 promoter mutants. (A) Nucleosome occupancy profile of HSC82 promoter: note the pronounced NFR. (B) Noise versus mean expression of mutants of the HSC82 library. Mutants form two branches on the noise–mean plane. Mutants from the upper and lower branch were sequenced (blue and green, respectively). (R) Mutation in Reb1 binding; (T) mutation in the TATA box; (H) mutation in the HSF1 binding site. (Error bars) Standard error of three biological repeats.
