Sex-biased genetic effects on gene regulation in humans

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Figure 1.
Figure 1.

Comparison of female (x-axis) versus male (y-axis) expression medians. Log2 expression medians were compared across the sexes for (A) all genes, (B) eQTL-genes, (C) TBSD eQTL-genes, and (D) sex-biased eQTL-genes. In all cases, the correlation between log2 expression levels in females and males was found to be very high (r2 = 0.99 and p < 10−4), suggesting that expression level differences between sexes are not the primary driver of eQTL discovery.

This Article

  1. Published in Advance September 7, 2012, doi: 10.1101/gr.134981.111 Genome Res. 22: 2368-2375

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