Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer

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Figure 3.
Figure 3.

Novel candidate driver cancer genes identified by shRNA screening in Ba/F3 viability assay. (A) Ba/F3 cells were transfected with short-hairpin RNAs (shRNA) targeting indicated genes. Empty vector (pGIPZ) and nonspecific shRNA served as the control. Cells were cultured without IL-3 for 4 wk and harvested for viability assay. Cell viability relative to Ba/F3 parental cells was shown. (*) P < 0.05, compared with Ba/F3 parental control. (B) Whole cell lysates were also collected for Western blotting with indicated antibodies, and ERK2 was used as the loading control.

This Article

  1. Published in Advance October 1, 2012, doi: 10.1101/gr.137596.112 Genome Res. 22: 2120-2129

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