See original article: Robinson et al. 20 (12): 1719.

Erratum

Genome Research 20: 1719–1729 (2010)

Evaluation of affinity-based genome-wide DNA methylation data: Effects of CpG density, amplification bias, and copy number variation

Mark D. Robinson, Clare Stirzaker, Aaron L. Statham, Marcel W. Coolen, Jenny Z. Song, Shalima S. Nair, Dario Strbenac, Terence P. Speed, and Susan J. Clark

Panels A and B in Figure 7 were incorrectly reversed in the text and the figure legend. The corrected text and legend are as follows:

The first full sentence in the top left column of page 1725 should read as follows:

Figure 7B illustrates changes in MBDCap-seq read counts along chromosome 13. As expected, they are correlated with changes in copy number (Fig. 7A) for the same regions.

The corrected figure legend should read as follows:

Figure 7.

Effects of copy number changes on differential methylation detection. (A) Smoothed Affymetrix SNP 6.0 array data showing corresponding changes in copy number for human chromosome 13. (B) Differential methylation Z-score between LNCaP and PrEC cells, using MBD-SF-seq. (C) Genome-wide distributions of Z-scores, stratified by the change-in-copy-number status of the corresponding regions.

The authors apologize for any confusion this may have caused.

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