Andy Lin; Richard T. Wang; Sangtae Ahn; Christopher C. Park; Desmond J. Smith

A genome-wide map of human genetic interactions inferred from radiation hybrid genotypes

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Figure 5.

Network topology. (A) Subnetwork of gene COX1 (PTGS1) and all genes up to two edges away at FDR <10⁻⁶. (B) Subnetwork of gene MTOR (FRAP1) and all genes up to three edges away at FDR <10⁻⁸. (C) Degree distribution of fully combined RH network at FDR <5%. Number of degrees, k, and point probability of node with k degrees, P(k), plotted on log scales. (D) Degree distribution of HPRD network. (E) Degree distribution of fully combined RH network at FDR <10⁻⁸.