Cover image
Cover An illustration depicting a reflection reminiscent of twins highlights a study in this issue that demonstrates the potential role of epigenetic changes in autoimmune disease. The authors report that monozygotic twins discordant for systemic lupus erythematosus (SLE) show DNA methylation and expression changes in genes relevant to SLE pathogenesis. (Original artwork “La mirada innumerable de Narcís”/“The innumerable look of Narcissus” [2003; charcoal on canvas], by Manuel Boix, http://www.manuelboix.com. [For details, see Javierre et al., pp. 170–179.])
