Coexpression network based on natural variation in human gene expression reveals gene interactions and functions

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Figure 5.
Figure 5.

TRAF1 and HMGCR subnetworks. (A) This subnetwork consists of TRAF1 (center, gray) and 20 direct neighbors. To simplify the figure, only the top 20 genes that are most correlated in expression with TRAF1 are shown even though TRAF1 has 56 neighbors. CD40, TNFAIP3, and TRAF1 have been implicated in the pathogenesis of rheumatoid arthritis and are marked with star symbols. (B) This subnetwork consists of HMGCR (center, gray) and its direct neighbors.

This Article

  1. Published in Advance October 1, 2009, doi: 10.1101/gr.097600.109 Genome Res. 19: 1953-1962

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