Figure 2.
Assessment of the technical reproducibility observed for the BiMP technology. A scatter plot comparison of two technically replicated hybridization datasets (one hybridization per axis) with all signal intensities presented (>3.2 × 106 probe pairs, log2 scale). From one bisulfite-converted sample, two DNA aliquots (100 ng) were independently amplified, fragmented, labeled, and hybridized (see Methods). The correlation coefficient (r) was calculated using TAS (Affymetrix), and the plot was drawn in the R statistical environment (http://www.r-project.org). (A) Col bisulfite-converted DNA, (B) met1-3 bisulfite-converted DNA.
