Cover image
Cover An H & E stain illustrating the undulating pattern of crypts and villi from the proximal small intestine of a C57BL/6J ApcMin/+ mouse compared to the sequence of a portion of exon 3 from the Atp5a1 gene isolated from a Mom2R/+ mouse. The chromatograph displays the 4 base pair duplication found in exon 3 of the Atp5a1 gene, the candidate gene for the modifier of Min 2 (Mom2) locus. The Mom2R mutation suppresses intestinal polyposis by ~90% in ApcMin/+ mice. (Cover illustration by Amy A. Baran and Arthur M. Buchberg. [For details, see Baran et al., pp. 566-576.])
