Volume 16, Issue 5 | May 2006

PERSPECTIVE
- - Embracing the complexity of genomic data for personalized medicine
    Mike West
    Geoffrey S. Ginsburg
    Andrew T. Huang
    Joseph R. Nevins
    First Published May 1, 2006
ARTICLE
- - A genome-wide distribution of 8-oxoguanine correlates with the preferred regions for recombination and single nucleotide polymorphism in the human genome
    Mizuki Ohno
    Tomofumi Miura
    Masato Furuichi
    Yohei Tominaga
    Daisuke Tsuchimoto
    First Published May 1, 2006
LETTERS
- - A preliminary comparative analysis of primate segmental duplications shows elevated substitution rates and a great-ape expansion of intrachromosomal duplications
    Xinwei She
    Ge Liu
    Mario Ventura
    Shaying Zhao
    Doriana Misceo
    Roberta Roberto Maria Francesca Cardone
    ...[+2 authors]...,
    Mariano Rocchi
    Eric D. Green
    Nicoletta Archidiacano
    Evan E. Eichler
    First Published April 10, 2006
  - Evolutionary expansion and divergence in the ZNF91 subfamily of primate-specific zinc finger genes
    Aaron T. Hamilton
    Stuart Huntley
    Mary Tran-Gyamfi
    Daniel M. Baggott
    Laurie Gordon
    First Published April 10, 2006
  - Unbiased location analysis of E2F1-binding sites suggests a widespread role for E2F1 in the human genome
    Mark Bieda
    Xiaoqin Xu
    Michael A. Singer
    Roland Green
    Peggy J. Farnham
    First Published April 10, 2006
  - Conservation and functional significance of gene topology in the genome of Caenorhabditis elegans
    Nansheng Chen
    Lincoln D. Stein
    First Published April 10, 2006
  - Haplotype variation in structure and expression of a gene cluster associated with a quantitative trait locus for improved yield in rice
    Guangming He
    Xiaojin Luo
    Feng Tian
    Kegui Li
    Zuofeng Zhu
    Wei Su Xiaoyin Qian
    ...[+2 authors]...,
    Yongcai Fu
    Xiangkun Wang
    Chuanqing Sun
    Jinshui Yang
    First Published April 10, 2006
  - Integrated analysis of regulatory and metabolic networks reveals novel regulatory mechanisms in Saccharomyces cerevisiae
    Markus J. Herrgård
    Baek-Seok Lee
    Vasiliy Portnoy
    Bernhard Ø. Palsson
    First Published April 10, 2006
  - The fate of laterally transferred genes: Life in the fast lane to adaptation or death
    Weilong Hao
    G. Brian Golding
    First Published May 1, 2006
  - Genome-wide prediction of G4 DNA as regulatory motifs: Role in Escherichia coli global regulation
    Pooja Rawal
    Veera Bhadra Rao Kummarasetti
    Jinoy Ravindran
    Nirmal Kumar
    Kangkan Halder
    First Published May 1, 2006
Methods
- - Genome-wide computational prediction of transcriptional regulatory modules reveals new insights into human gene expression
    Mathieu Blanchette
    Alain R. Bataille
    Xiaoyu Chen
    Christian Poitras
    Josée Laganière
    Céline Lefèbvre Geneviève Deblois Vincent Giguère
    ...[+3 authors]...,
    Vincent Ferretti
    Dominique Bergeron
    Benoit Coulombe
    François Robert
    First Published April 10, 2006
RESOURCES
- - A comprehensive catalog of human KRAB-associated zinc finger genes: Insights into the evolutionary history of a large family of transcriptional repressors
    Stuart Huntley
    Daniel M. Baggott
    Aaron T. Hamilton
    Mary Tran-Gyamfi
    Shan Yang
    First Published April 10, 2006
  - Iterative gene prediction and pseudogene removal improves genome annotation
    Marijke J. van Baren
    Michael R. Brent
    First Published May 1, 2006
  - Large-scale identification of protein–protein interaction of Escherichia coli K-12
    Mohammad Arifuzzaman
    Maki Maeda
    Aya Itoh
    Kensaku Nishikata
    Chiharu Takita
    Rintaro Saito Takeshi Ara Kenji Nakahigashi Hsuan-Cheng Huang Aki Hirai Kohei Tsuzuki Seira Nakamura Mohammad Altaf-Ul-Amin Taku Oshima Tomoya Baba Natsuko Yamamoto Tomoyo Kawamura Tomoko Ioka-Nakamichi Masanari Kitagawa
    ...[+14 authors]...,
    Masaru Tomita
    Shigehiko Kanaya
    Chieko Wada
    Hirotada Mori
    First Published April 10, 2006

Table of Contents

Volume 16, Issue 5 | May 2006

PERSPECTIVE

Embracing the complexity of genomic data for personalized medicine

ARTICLE

A genome-wide distribution of 8-oxoguanine correlates with the preferred regions for recombination and single nucleotide polymorphism in the human genome

LETTERS

A preliminary comparative analysis of primate segmental duplications shows elevated substitution rates and a great-ape expansion of intrachromosomal duplications

Evolutionary expansion and divergence in the ZNF91 subfamily of primate-specific zinc finger genes

Unbiased location analysis of E2F1-binding sites suggests a widespread role for E2F1 in the human genome

Conservation and functional significance of gene topology in the genome of Caenorhabditis elegans

Haplotype variation in structure and expression of a gene cluster associated with a quantitative trait locus for improved yield in rice

Integrated analysis of regulatory and metabolic networks reveals novel regulatory mechanisms in Saccharomyces cerevisiae

The fate of laterally transferred genes: Life in the fast lane to adaptation or death

Genome-wide prediction of G4 DNA as regulatory motifs: Role in Escherichia coli global regulation

Methods

Genome-wide computational prediction of transcriptional regulatory modules reveals new insights into human gene expression

RESOURCES

A comprehensive catalog of human KRAB-associated zinc finger genes: Insights into the evolutionary history of a large family of transcriptional repressors

Iterative gene prediction and pseudogene removal improves genome annotation

Large-scale identification of protein–protein interaction of Escherichia coli K-12

Table of Contents

Volume 16, Issue 5 | May 2006

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PERSPECTIVE

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LETTERS

Methods

RESOURCES