Table 1.
Accuracy in classifications of variants assayed in four mutagenesis experiments
|
|
Positive vs. deleterious |
Intermediate vs. negative |
||||
|---|---|---|---|---|---|---|
|
|
MAPP |
SIFT |
Increase |
MAPP |
||
| HIV protease | 80.4% | 78.6% | 1.8% | 76.7% | ||
| LacI | 69.2% | 67.9% | 1.3% | 74.5% | ||
| HIV RT | 64.1% | 55.0% | 9.1% | 72.9% | ||
| T4 lysozyme
|
73.0%
|
68.3%
|
4.7%
|
62.6%
|
||
