Comparative FISH results
|
Duplicon location |
Duplicon name |
Probe type |
Probe name |
HSA |
PTR |
GGO |
PPY |
PHA |
MFA |
|---|---|---|---|---|---|---|---|---|---|
| 7p12b | PIR4 | 22 cosmid | N20B5 | 1p, 1q, 2cen, 7cen, 9p, 10q, 13p, 14p, 15p, 16p, 17p, 18p, 21q, 22q | 1p, 2p, 2q, 7cen, 10cen, 16cen | 16p | 7q | no signal | nd |
| 11q14 | 11q | 11 cosmid | 25122 | 11q | 11 | 11 | 11, 14, 21 | no signal | nd |
| 12p11 | 12p | nd | nd | nd | nd | nd | nd | nd | nd |
| 22q11 | Igλ | nd | nd | nd | nd | nd | nd | nd | nd |
| 22q12 | CHK2 | 22 cosmid | N5e10 | 16p, 22 | 16p, 22 | 16p, 16q, 22 | 21, 22 | no signal | nd |
| 4q24a | 4q24 | RPCI-11 BAC | 289C17 | 2p11, 4q24, 14p11, 10q11, 16p11, 22q11, Yq11 | 4q24, 10q11, 16p11, 22q11 | 4q24, 10q11, 16p11 | 4q24 | nd | 4q24 |
| xq28a | ALD | LR-PCR probe | ALD9.7 | 2p11, 10q11, 16p11, 22q11, Xq28 | 10q11, 16p11, 22q11, Xq28 | 2p11, 10q11, 14q11, 16p11(2x), Xq28 | Xq28 | nd | Xq28 |
| 22q11 | GGT1 | 22 cosmid | N24g22 | 22q | 22q | 2p, 2q, 9, 21, 22q | 2q, 22q | 22 | nd |
| 1p13 | IGSF3 | 1 cosmid | AH27b17 | 1p, 2, 13 | 1, 2p | 1, 2p, 9, 13, 15, 18, 21, 22 | 1 | nd | 1 |
| 10q26 | 10q26 | nd | nd | nd | nd | nd | nd | nd | nd |
| 7q36 | MLL3 | 7 cosmid | Y54g1 | 1q, 2q, 7qter, 13 (1 signal), 21 | 7 ter | 9 | 7q, 7qter | no signal | nd |
| 4p16.1 | 4p16.1 | RPCI-11 BAC | 751L19 | 4p16.1 | nd | nd | 4p16.1 | 4p16.1 | nd |
| 11p15 | LSP1 | nd | nd | nd | nd | nd | nd | nd | nd |
| 4p16.3
|
4p16.3
|
RPCI-11 BAC
|
265O12
|
4p16.3
|
nd
|
nd
|
4p16.3
|
4p16.3
|
nd
|
-
Cosmid, BAC and long-range PCR (LR-PCR) probes corresponding to each duplicon were hybridized to metaphase chromosome preparations of a variety of primate species. FISH results are indicated for HSA (H. sapiens), PTR (P. troglodytes), GGO (G. gorilla), PPY (P. pygmaeus), PHA (P. hamadryas), and MFA (M. fascicularis). An “nd” signifies that hybridization was not done because duplicon length was too short or the copy number was too great to obtain reliable estimates by FISH. A report of “no signal” meant that no hybridization signal was detected after FISH. All signals are pericentromeric unless noted. All chromosomal designations indicated are with respect to the human phylogenetic group (McConkey, 2004).
-
↵a Information for duplicons 4q24, and ALD was previously published in Horvath et al., 2000b
-
↵b PIR4 results were previously published in Horvath et al., 2003
