Julie E. Horvath; Cassandra L. Gulden; Rhea U. Vallente; Marla Y. Eichler; Mario Ventura; John D. McPherson; Tina A. Graves; Richard K. Wilson; Stuart Schwartz; Mariano Rocchi; Evan E. Eichler

Table 1.

2p11 Duplicon sequence properties

Ancestral location	Duplicon name	Build 34 alignments	Ancestral chromosome	Build 34 begin	Build 34 end	Paralogous chr2	Build 34 begin	Build 34 end	Alignment length (bp)	Percent identity	Repeat
7p12	pir4	50	chr7	52931091	52953785	chr2	91716578	91738986	23046	94.0
11q14	11q	7	chr11	89568972	89571044	chr2	91699117	91701188	2091	95.1
11q14	11q	9	chr11	89519459	89539156	chr2	91679227	91699086	21099	94.1
12p11	12p	8	chr12	27307033	27314333	chr2	91673194^a	91679108	7350	94.9	AluSq
22q11	lgλ	32	chr22	20948276	20976056	chr2	91651635	91673445^a	28411	95.8
22q12	CHK2	13	chr22	27396207	27415189	chr2	91629693^b	91651630	22155	95.2
4q24	4q24	5	chr4	104340868	104356278	chr2	91612384	91629698^b	17360	95.6
4q24	4q24	5	chr4	104329872	104338171	chr2	91606549^a	91612376	8365	95.8
4q24	4q24	5	chr4	104322271	104328805	chr2	91600337	91606554^a	6691	95.8	L1PA15, AluSg
4q24	4q24	7	chr4	104276520	104319279	chr2	91551291	91593954	42964	95.8
4q24	4q24	6	chr4	104266506	104276513	chr2	91531378	91541381	10067	96.4
Xq28	ALD	5	chrX	151473852	151483609	chr2	91513314	91523079	9842	95.7
11q14	11q	9	chr11	89525311	89539156	chr2	91499241	91512571	14527	95.2
11q14	11q	7	chr11	89568972	89571044	chr2	91497139	91499210	2091	95.1
7p12	PIR4	50	chr7	52931091	52955315	chr2	91457832	91481757	24575	94.0
22q11	GGT1	5	chr22	23337169	23343213	chr2	91449527^a	91455557	6051	96.7
22q11	GGT1	5	chr22	23322945	23332600	chr2	91441101	91449696^a	9669	97.2	AluSg
1p13	IGSF3	2	chr1	116476821	116495886	chr2	91422050	91441097	19108	97.5
1p13	IGSF3	4	chr1	116495873	116512648	chr2	91402369^a	91419084	16828	97.1
10q26	10q26	4	chr10	127182300	127187515	chr2	91397399	91402574^a	5259	97.0	AluSc
7q36	MLL3	7	chr7	151300710	151330205	chr2	91360615^a	91390058	29629	97.1
4p16.1	4p16.1	2	chr4	9531944	9552677	chr2	91340328	91360773^a	21014	95.3	AluY
11p15	11p15	2	chr11	1859940	1863883	chr2	91328768	91332730	3973	94.8
11p15	11p15	2	chr11	1871783	1872884	chr2	91327670	91328767	1101	96.8
7q36	MLL3	2	chr7	151386594	151392806	chr2	91318140	91324329	6226	96.9
4p16.1	4p16.1	2	chr4	9512955	9532432	chr2	91301404	91318132	95141	99.2
4p16.3	4p16.3	1	chr4	4248063	4268960	chr2	91280163^a	91300737	21155	95.1
4p16.3	4p16.3	1	chr4	4274738	4306539	chr2	91248931	91280164^a	32160	95.2	L1MB2
22q11	lgλ	36	chr22	20936002	20979439	chr2	91200069	91238134	44479	97.2

Ancestral positions of all duplicons > 5 kb in total are indicated.

Putative ancestral chromosomal location and copy number (build34) of all duplicons found within 2p11 are shown. The percentage identity between the ancestral and duplicated copy on chromosome 2p11 was calculated. Occasionally, a duplicon termination point occurs within a high copy repeat (as indicated on the far right) and appears to overlap another duplicon termination point as a result.
↵a Chr2 end position of one duplicon overlaps with the chr2 begin position of the adjacent duplicon due to termination within a repeat element (LINE or SINE)
↵b Chr2 begin and end positions overlapped by 5 bp

Punctuated duplication seeding events during the evolution of human chromosome 2p11

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