The function and expansion of the Patched- and Hedgehog-related homologs in C. elegans

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Figure 4.
Figure 4.

Elimination of ptr or hh-r gene activity by RNAi causes defects in adult alae formation. (A) Wild-type alae in N2. (BD) Defective alae produced by RNAi of ptr or hh-r gene members. (B) Discontinuous alae (arrowheads). (C) Bifurcated alae. (D) Multiply branched alae. (C, D) Multiple alae composed of four instead of three cuticle ridges. (E) Summary of alae defects after RNAi of ptr or hh-r genes. All genes displayed in Tables 1 and 2 were examined; however, only those showing phenotypes are displayed. Scale bar, 10 μm.

This Article

  1. Genome Res. 15: 1402-1410

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