Figure 3.
Disruption of ptc and ptr genes by RNAi leads to growth and developmental defects. (A)A ptr-4(RNAi) adult hermaphrodite (bottom) is 30% shorter than is a similarly staged wild-type hermaphrodite (top). (B) An everted vulva in a ptr-11(RNAi) animal. (C) ptr-1(RNAi) animals accumulate fluid-filled vacuoles in the hypodermis. (D) Blisters caused by ptr-3(RNAi). (E) Summary of phenotypes produced by RNAi, not including molting. All the ptc and ptr genes were examined; however, only those showing RNAi phenotypes are displayed. Scale bar, 50 μm.
