High-Resolution Analysis of DNA Copy Number Using Oligonucleotide Microarrays

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Figure 1
Figure 1

Plot of log(copy number) against log(intensity) for the spiking experiment in which 18 aliquots of the same DNA were spiked with varying concentrations of 42 SNPs from twofold up to 1000-fold. The black dots indicate the results for the individual SNPs across the 12 spiking concentrations (spiked with an extra 0, 2, 5, 10, 25, 50, 75, 100, 250, 500, 750, and 1000 copies); the green dots and line show the mean for all 42 SNPs. Two SNPs did not report increased fluorescence with increased copy number, and these are highlighted in red.

This Article

  1. Genome Res. 14: 287-295

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