Analysis of Sequence Variations in Several Human Genes Using Phosphoramidite Bond DNA Fragmentation and Chip-Based MALDI-TOF

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Figure 5
Figure 5

Incomplete (partial) P-N-bond cleavage. APOB extension product (265 bp) was generated as in Figure 2B with the exception that 10 μM natural dTTP was incorporated together with 5 mM P-N dTTP. Note the increased total number of fragmentation peaks compared with Figure 2B. Representative incomplete cleavage peaks are labeled by a crossed circle.

This Article

  1. Genome Res. 14: 134-141

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