Extrachromosomal Circular DNA of Tandemly Repeated Genomic Sequences in Drosophila

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Figure 8
Figure 8

Absence of eccDNA homologous to the dispersed P element. (A) A 2D-gel blot of wild-type (π2) adult DNA, hybridized with a cloned 5′ region of the P transposable element, reveals only the linear arc. (B) Rehybridization of this blot with a total genomic DNA probe reveals both the arc of eccDNA and the arc of linear DNA, indicating that the absence of the eccDNA arc in panel A reflects the absence of P-element sequences within the eccDNA population.

This Article

  1. Genome Res. 13: 1133-1145

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